Human LCAT activation kit by CRISPRa

CAT#: GA102665

LCAT CRISPRa kit - CRISPR gene activation of human lecithin-cholesterol acyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LCAT
• Locus ID: 3931
• Kit Components:

  GA102665G1, LCAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102665G2, LCAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102665G3, LCAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000229
• Synonyms: lecithin-cholesterol acyltransferase
• Summary: 'This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008]'