Human LETM1 activation kit by CRISPRa

CAT#: GA102679

LETM1 CRISPRa kit - CRISPR gene activation of human leucine zipper and EF-hand containing transmembrane protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LETM1
• Locus ID: 3954
• Kit Components:

  GA102679G1, LETM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102679G2, LETM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102679G3, LETM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012318
• Synonyms: leucine zipper-EF-hand containing transmembrane protein 1
• Summary: 'This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009]'