Human Galectin 3 (LGALS3) activation kit by CRISPRa

CAT#: GA102683

LGALS3 CRISPRa kit - CRISPR gene activation of human galectin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LGALS3
• Locus ID: 3958
• Kit Components:

  GA102683G1, Galectin 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102683G2, Galectin 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102683G3, Galectin 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177388, NM_002306, NR_003225, NM_001357678
• Synonyms: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
• Summary: 'This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]'