Human LLGL1 activation kit by CRISPRa

CAT#: GA102709

LLGL1 CRISPRa kit - CRISPR gene activation of human LLGL scribble cell polarity complex component 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LLGL1
• Locus ID: 3996
• Kit Components:

  GA102709G1, LLGL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102709G2, LLGL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102709G3, LLGL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004140
• Synonyms: DLG4; HUGL; HUGL-1; HUGL1; LLGL
• Summary: 'This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]'