Human LTBP3 activation kit by CRISPRa

CAT#: GA102748

LTBP3 CRISPRa kit - CRISPR gene activation of human latent transforming growth factor beta binding protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LTBP3
• Locus ID: 4054
• Kit Components:

  GA102748G1, LTBP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102748G2, LTBP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102748G3, LTBP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130144, NM_001164266, NM_021070
• Synonyms: DASS; LTBP-3; LTBP2; pp6425; STHAG6
• Summary: 'The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]'