Human M6PR activation kit by CRISPRa

CAT#: GA102767

M6PR CRISPRa kit - CRISPR gene activation of human mannose-6-phosphate receptor, cation dependent

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: M6PR
• Locus ID: 4074
• Kit Components:

  GA102767G1, M6PR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102767G2, M6PR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102767G3, M6PR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001207024, NM_002355
• Synonyms: CD-MPR; MPR-46; MPR 46; MPR46; SMPR
• Summary: 'This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]'