Human SMAD5 activation kit by CRISPRa

CAT#: GA102778

SMAD5 CRISPRa kit - CRISPR gene activation of human SMAD family member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SMAD5
• Locus ID: 4090
• Kit Components:

  GA102778G1, SMAD5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102778G2, SMAD5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102778G3, SMAD5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001419, NM_001001420, NM_005903
• Synonyms: DWFC; JV5-1; MADH5
• Summary: 'The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]'