Human SMAD6 activation kit by CRISPRa

CAT#: GA102779

SMAD6 CRISPRa kit - CRISPR gene activation of human SMAD family member 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SMAD6
• Locus ID: 4091
• Kit Components:

  GA102779G1, SMAD6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102779G2, SMAD6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102779G3, SMAD6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142861, NM_005585, NR_027654
• Synonyms: AOVD2; HsT17432; MADH6; MADH7
• Summary: 'The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]'