Human MAG activation kit by CRISPRa

CAT#: GA102784

MAG CRISPRa kit - CRISPR gene activation of human myelin associated glycoprotein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAG
• Locus ID: 4099
• Kit Components:

  GA102784G1, MAG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102784G2, MAG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102784G3, MAG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199216, NM_002361, NM_080600
• Synonyms: GMA; S-MAG; SIGLEC-4A; SIGLEC4A
• Summary: 'The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]'