Human MAGEA8 activation kit by CRISPRa

CAT#: GA102791

MAGEA8 CRISPRa kit - CRISPR gene activation of human MAGE family member A8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAGEA8
• Locus ID: 4107
• Kit Components:

  GA102791G1, MAGEA8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102791G2, MAGEA8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102791G3, MAGEA8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166400, NM_001166401, NM_005364
• Synonyms: CT1.8; MAGE8
• Summary: 'This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]'