Human Myoglobin (MB) activation kit by CRISPRa

CAT#: GA102829

MB CRISPRa kit - CRISPR gene activation of human myoglobin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MB
• Locus ID: 4151
• Kit Components:

  GA102829G1, Myoglobin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102829G2, Myoglobin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102829G3, Myoglobin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005368, NM_203377, NM_203378, NM_001362846
• Synonyms: myoglobgin; PVALB
• Summary: 'This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric oxide. Multiple transcript variants encoding distinct isoforms exist for this gene. [provided by RefSeq, May 2020]'