Human MC3R activation kit by CRISPRa

CAT#: GA102836

MC3R CRISPRa kit - CRISPR gene activation of human melanocortin 3 receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MC3R
• Locus ID: 4159
• Kit Components:

  GA102836G1, MC3R gRNA vector 1 in pCas-Guide-CRISPRa

  GA102836G2, MC3R gRNA vector 2 in pCas-Guide-CRISPRa

  GA102836G3, MC3R gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019888
• Synonyms: BMIQ9; MC3; MC3-R; OB20; OQTL
• Summary: This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]