Human MCF2 activation kit by CRISPRa

CAT#: GA102842

MCF2 CRISPRa kit - CRISPR gene activation of human MCF.2 cell line derived transforming sequence

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MCF2
• Locus ID: 4168
• Kit Components:

  GA102842G1, MCF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102842G2, MCF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102842G3, MCF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099855, NM_001171876, NM_001171877, NM_001171878, NM_001171879, NM_005369
• Synonyms: ARHGEF21; DBL
• Summary: 'The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010]'