Human MDFI activation kit by CRISPRa

CAT#: GA102853

MDFI CRISPRa kit - CRISPR gene activation of human MyoD family inhibitor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MDFI
• Locus ID: 4188
• Kit Components:

  GA102853G1, MDFI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102853G2, MDFI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102853G3, MDFI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300804, NM_001300805, NM_001300806, NM_005586
• Synonyms: I-MF; I-mfa
• Summary: 'This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008]'