Human MEF2A activation kit by CRISPRa

CAT#: GA102864

MEF2A CRISPRa kit - CRISPR gene activation of human myocyte enhancer factor 2A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MEF2A
• Locus ID: 4205
• Kit Components:

  GA102864G1, MEF2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102864G2, MEF2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102864G3, MEF2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130926, NM_001130927, NM_001130928, NM_001171894, NM_005587, NM_001319206, NM_001352614, NM_001352615, NM_001352616, NM_001352617, NM_001352618, N93079, NM_001365204, NM_001365207, NM_001365208, NM_001365210, NM_001365201, NM_001365202, NM_001365203, NM_001365205, NM_001365206, NM_001365209, NM_001365211
• Synonyms: ADCAD1; mef2; RSRFC4; RSRFC9
• Summary: 'The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]'