Human METTL1 activation kit by CRISPRa

CAT#: GA102884

METTL1 CRISPRa kit - CRISPR gene activation of human methyltransferase like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: METTL1
• Locus ID: 4234
• Kit Components:

  GA102884G1, METTL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102884G2, METTL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102884G3, METTL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005371, NM_023032, NM_023033
• Synonyms: C12orf1; TRM8; TRMT8; YDL201w
• Summary: 'This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008]'