Human MGAT1 activation kit by CRISPRa

CAT#: GA102892

MGAT1 CRISPRa kit - CRISPR gene activation of human mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MGAT1
• Locus ID: 4245
• Kit Components:

  GA102892G1, MGAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102892G2, MGAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102892G3, MGAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114617, NM_001114618, NM_001114619, NM_001114620, NM_002406, NM_001364390, NR_157150, NR_157151, NM_001364379, NM_001364380, NM_001364384, NM_001364386, NM_001364388, NM_001364391, NM_001364392, NM_001364393, NM_001364394, NM_001364377, NM_001364381, NM_001364382, NM_001364383, NM_001364385, NM_001364387, NM_001364389, NM_001364395, NR_157152, NR_157153, NR_157154
• Synonyms: GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; MGAT
• Summary: 'There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'