Human MGAT5 activation kit by CRISPRa

CAT#: GA102896

MGAT5 CRISPRa kit - CRISPR gene activation of human alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MGAT5
• Locus ID: 4249
• Kit Components:

  GA102896G1, MGAT5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102896G2, MGAT5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102896G3, MGAT5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002410
• Synonyms: GNT-V; GNT-VA
• Summary: 'The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]'