Human MGST2 activation kit by CRISPRa

CAT#: GA102903

MGST2 CRISPRa kit - CRISPR gene activation of human microsomal glutathione S-transferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MGST2
• Locus ID: 4258
• Kit Components:

  GA102903G1, MGST2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102903G2, MGST2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102903G3, MGST2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204366, NM_001204367, NM_001204368, NM_002413
• Synonyms: GST2; MGST-II
• Summary: 'The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011]'