Human CD99 activation kit by CRISPRa

CAT#: GA102906

CD99 CRISPRa kit - CRISPR gene activation of human CD99 molecule (Xg blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD99
• Locus ID: 4267
• Kit Components:

  GA102906G1, CD99 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102906G2, CD99 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102906G3, CD99 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001122898, NM_001277710, NM_002414, NM_001321367, NM_001321368, NM_001321369, NM_001321370, NR_135623
• Synonyms: HBA71; MIC2; MIC2X; MIC2Y; MSK5X
• Summary: 'The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]'