Human Myeloid leukemia factor 1 (MLF1) activation kit by CRISPRa

CAT#: GA102917

MLF1 CRISPRa kit - CRISPR gene activation of human myeloid leukemia factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MLF1
• Locus ID: 4291
• Kit Components:

  GA102917G1, Myeloid leukemia factor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102917G2, Myeloid leukemia factor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102917G3, Myeloid leukemia factor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130156, NM_001130157, NM_001195432, NM_001195433, NM_001195434, NM_022443, NM_001369782, NM_001369784, NM_001369781, NM_001369783, NM_001369785
• Synonyms: myeloid leukemia factor 1; myeloid leukemia factor 1 variant 1; myeloid leukemia factor 1 variant 2; myeloid leukemia factor 1 variant 3
• Summary: 'This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]'