Human FOXO4 activation kit by CRISPRa

CAT#: GA102929

FOXO4 CRISPRa kit - CRISPR gene activation of human forkhead box O4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXO4
• Locus ID: 4303
• Kit Components:

  GA102929G1, FOXO4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102929G2, FOXO4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102929G3, FOXO4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001170931, NM_005938
• Synonyms: AFX; AFX1; MLLT7
• Summary: 'This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]'