Human MNAT1 activation kit by CRISPRa

CAT#: GA102950

MNAT1 CRISPRa kit - CRISPR gene activation of human MNAT1 component of CDK activating kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MNAT1
• Locus ID: 4331
• Kit Components:

  GA102950G1, MNAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102950G2, MNAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102950G3, MNAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177963, NM_002431
• Synonyms: CAP35; MAT1; RNF66; TFB3
• Summary: 'The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]'