Human MPP3 activation kit by CRISPRa

CAT#: GA102966

MPP3 CRISPRa kit - CRISPR gene activation of human membrane palmitoylated protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MPP3
• Locus ID: 4356
• Kit Components:

  GA102966G1, MPP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102966G2, MPP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102966G3, MPP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330233, NM_001932, NR_003562, NM_001353080, NR_148342, NR_148343, NR_148344, NR_148345
• Synonyms: DLG3
• Summary: 'This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]'