Human MSX2 activation kit by CRISPRa

CAT#: GA102993

MSX2 CRISPRa kit - CRISPR gene activation of human msh homeobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MSX2
• Locus ID: 4488
• Kit Components:

  GA102993G1, MSX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102993G2, MSX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102993G3, MSX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002449, NM_001363626
• Synonyms: CRS2; FPP; HOX8; MSH; PFM; PFM1
• Summary: 'This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]'