Human MTAP activation kit by CRISPRa

CAT#: GA103004

MTAP CRISPRa kit - CRISPR gene activation of human methylthioadenosine phosphorylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MTAP
• Locus ID: 4507
• Kit Components:

  GA103004G1, MTAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103004G2, MTAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103004G3, MTAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002451
• Synonyms: BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP
• Summary: 'This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]'