Human MTF1 activation kit by CRISPRa

CAT#: GA103012

MTF1 CRISPRa kit - CRISPR gene activation of human metal regulatory transcription factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MTF1
• Locus ID: 4520
• Kit Components:

  GA103012G1, MTF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103012G2, MTF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103012G3, MTF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005955
• Synonyms: MTF-1; ZRF
• Summary: 'This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008]'