Human MUSK activation kit by CRISPRa

CAT#: GA103040

MUSK CRISPRa kit - CRISPR gene activation of human muscle associated receptor tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MUSK
• Locus ID: 4593
• Kit Components:

  GA103040G1, MUSK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103040G2, MUSK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103040G3, MUSK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166280, NM_001166281, NM_005592, NM_001369398
• Synonyms: MGC126323; MGC126324
• Summary: 'This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009]'