Human B MyB (MYBL2) activation kit by CRISPRa

CAT#: GA103051

MYBL2 CRISPRa kit - CRISPR gene activation of human MYB proto-oncogene like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYBL2
• Locus ID: 4605
• Kit Components:

  GA103051G1, B MyB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103051G2, B MyB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103051G3, B MyB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278610, NM_002466
• Synonyms: B-MYB; BMYB
• Summary: 'The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]'