Human Myosin Light Chain 2 (MYL2) activation kit by CRISPRa

CAT#: GA103073

MYL2 CRISPRa kit - CRISPR gene activation of human myosin light chain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYL2
• Locus ID: 4633
• Kit Components:

  GA103073G1, Myosin Light Chain 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103073G2, Myosin Light Chain 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103073G3, Myosin Light Chain 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000432
• Synonyms: CMH10; MLC-2s/v; MLC2
• Summary: 'Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]'