Human MYOD1 activation kit by CRISPRa

CAT#: GA103092

MYOD1 CRISPRa kit - CRISPR gene activation of human myogenic differentiation 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYOD1
• Locus ID: 4654
• Kit Components:

  GA103092G1, MYOD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103092G2, MYOD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103092G3, MYOD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002478
• Synonyms: bHLHc1; MYF3; MYOD; PUM
• Summary: 'This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]'