Human NAP1L4 activation kit by CRISPRa

CAT#: GA103108

NAP1L4 CRISPRa kit - CRISPR gene activation of human nucleosome assembly protein 1 like 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAP1L4
• Locus ID: 4676
• Kit Components:

  GA103108G1, NAP1L4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103108G2, NAP1L4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103108G3, NAP1L4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005969, NM_001369375, NM_001369377, NM_001369379, NM_001369383, NM_001369384, NM_001369386, NM_001369376, NM_001369378, NM_001369380, NM_001369381, NM_001369382, NM_001369385, NM_001369388
• Synonyms: hNAP2; NAP1L4b; NAP2; NAP2L
• Summary: 'This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]'