NAP1L4 Human Gene Knockout Kit (CRISPR)

CAT#: KN401407

NAP1L4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: NAP1L4
• Locus ID: 4676
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_005969, NM_001369375, NM_001369377, NM_001369379, NM_001369383, NM_001369384, NM_001369386, NM_001369376, NM_001369378, NM_001369380, NM_001369381, NM_001369382, NM_001369385, NM_001369388
• Synonyms: hNAP2; NAP1L4b; NAP2; NAP2L
• Summary: 'This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]'