Human NDP activation kit by CRISPRa

CAT#: GA103123

NDP CRISPRa kit - CRISPR gene activation of human norrin cystine knot growth factor NDP

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDP
• Locus ID: 4693
• Kit Components:

  GA103123G1, NDP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103123G2, NDP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103123G3, NDP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000266
• Synonyms: EVR2; FEVR; ND
• Summary: 'This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq, Feb 2009]'