Human NDUFA2 activation kit by CRISPRa

CAT#: GA103125

NDUFA2 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFA2
• Locus ID: 4695
• Kit Components:

  GA103125G1, NDUFA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103125G2, NDUFA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103125G3, NDUFA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001185012, NM_002488, NR_033697
• Synonyms: B8; CD14; CIB8
• Summary: 'The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]'