Human NDUFB3 activation kit by CRISPRa

CAT#: GA103138

NDUFB3 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit B3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFB3
• Locus ID: 4709
• Kit Components:

  GA103138G1, NDUFB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103138G2, NDUFB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103138G3, NDUFB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001257102, NM_002491
• Synonyms: B12; CI-B12
• Summary: 'This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]'