Human NDUFV2 activation kit by CRISPRa

CAT#: GA103156

NDUFV2 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase core subunit V2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFV2
• Locus ID: 4729
• Kit Components:

  GA103156G1, NDUFV2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103156G2, NDUFV2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103156G3, NDUFV2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021074
• Synonyms: CI-24k
• Summary: 'The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]'