Human NEK2 activation kit by CRISPRa

CAT#: GA103169

NEK2 CRISPRa kit - CRISPR gene activation of human NIMA related kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEK2
• Locus ID: 4751
• Kit Components:

  GA103169G1, NEK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103169G2, NEK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103169G3, NEK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204182, NM_001204183, NM_002497
• Synonyms: HsPK21; NEK2A; NLK1; PPP1R111; RP67
• Summary: 'This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]'