Human NEUROD2 activation kit by CRISPRa

CAT#: GA103176

NEUROD2 CRISPRa kit - CRISPR gene activation of human neuronal differentiation 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEUROD2
• Locus ID: 4761
• Kit Components:

  GA103176G1, NEUROD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103176G2, NEUROD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103176G3, NEUROD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006160
• Synonyms: bHLHa1; NDRF
• Summary: 'This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq, Jul 2008]'