Human NFAT4 (NFATC3) activation kit by CRISPRa

CAT#: GA103183

NFATC3 CRISPRa kit - CRISPR gene activation of human nuclear factor of activated T cells 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NFATC3
• Locus ID: 4775
• Kit Components:

  GA103183G1, NFAT4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103183G2, NFAT4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103183G3, NFAT4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004555, NM_173163, NM_173164, NM_173165
• Synonyms: NFAT4; NFATX
• Summary: 'The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]'