Human NFIL3 activation kit by CRISPRa

CAT#: GA103190

NFIL3 CRISPRa kit - CRISPR gene activation of human nuclear factor, interleukin 3 regulated

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NFIL3
• Locus ID: 4783
• Kit Components:

  GA103190G1, NFIL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103190G2, NFIL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103190G3, NFIL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289999, NM_001290000, NM_005384
• Synonyms: E4BP4; IL3BP1; NF-IL3A; NFIL3A
• Summary: 'The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]'