Human NFYC activation kit by CRISPRa

CAT#: GA103203

NFYC CRISPRa kit - CRISPR gene activation of human nuclear transcription factor Y subunit gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NFYC
• Locus ID: 4802
• Kit Components:

  GA103203G1, NFYC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103203G2, NFYC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103203G3, NFYC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142587, NM_001142588, NM_001142589, NM_001142590, NM_001308114, NM_001308115, NM_014223
• Synonyms: CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC
• Summary: 'This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]'