Human NGF activation kit by CRISPRa

CAT#: GA103204

NGF CRISPRa kit - CRISPR gene activation of human nerve growth factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NGF
• Locus ID: 4803
• Kit Components:

  GA103204G1, NGF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103204G2, NGF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103204G3, NGF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002506
• Synonyms: Beta-NGF; HSAN5; NGFB
• Summary: 'This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]'