Human NHLH1 activation kit by CRISPRa

CAT#: GA103206

NHLH1 CRISPRa kit - CRISPR gene activation of human nescient helix-loop-helix 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NHLH1
• Locus ID: 4807
• Kit Components:

  GA103206G1, NHLH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103206G2, NHLH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103206G3, NHLH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005598
• Synonyms: bHLHa35; HEN1; NSCL; NSCL1
• Summary: 'The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002]'