Human Nkx3.1 (NKX3-1) activation kit by CRISPRa

CAT#: GA103217

NKX3-1 CRISPRa kit - CRISPR gene activation of human NK3 homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NKX3-1
• Locus ID: 4824
• Kit Components:

  GA103217G1, Nkx3.1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103217G2, Nkx3.1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103217G3, Nkx3.1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256339, NM_006167, NR_046072
• Synonyms: BAPX2; NKX3; NKX3.1; NKX3A
• Summary: 'This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]'