Human NME4 activation kit by CRISPRa

CAT#: GA103225

NME4 CRISPRa kit - CRISPR gene activation of human NME/NM23 nucleoside diphosphate kinase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NME4
• Locus ID: 4833
• Kit Components:

  GA103225G1, NME4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103225G2, NME4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103225G3, NME4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286433, NM_001286435, NM_001286436, NM_001286438, NM_001286439, NM_001286440, NM_005009
• Synonyms: NDPK-D; nm23-H4; NM23H4
• Summary: 'The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 [PubMed 9099850]).[supplied by OMIM, May 2008]'