Human NQO2 activation kit by CRISPRa

CAT#: GA103226

NQO2 CRISPRa kit - CRISPR gene activation of human N-ribosyldihydronicotinamide:quinone reductase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NQO2
• Locus ID: 4835
• Kit Components:

  GA103226G1, NQO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103226G2, NQO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103226G3, NQO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000904, NM_001290221, NM_001290222, NM_001318940
• Synonyms: DHQV; DIA6; NMOR2; QR2
• Summary: 'This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'