Human iNOS (NOS2) activation kit by CRISPRa

CAT#: GA103233

NOS2 CRISPRa kit - CRISPR gene activation of human nitric oxide synthase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NOS2
• Locus ID: 4843
• Kit Components:

  GA103233G1, iNOS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103233G2, iNOS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103233G3, iNOS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000625, NM_153292
• Synonyms: HEP-NOS; INOS; NOS; NOS2A
• Summary: 'Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]'