Human NPY5R activation kit by CRISPRa

CAT#: GA103265

NPY5R CRISPRa kit - CRISPR gene activation of human neuropeptide Y receptor Y5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPY5R
• Locus ID: 4889
• Kit Components:

  GA103265G1, NPY5R gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103265G2, NPY5R gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103265G3, NPY5R gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317091, NM_001317092, NM_006174
• Synonyms: NPY5-R; NPYR5; NPYY5-R
• Summary: 'The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]'