Human NRF1 activation kit by CRISPRa

CAT#: GA103271

NRF1 CRISPRa kit - CRISPR gene activation of human nuclear respiratory factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NRF1
• Locus ID: 4899
• Kit Components:

  GA103271G1, NRF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103271G2, NRF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103271G3, NRF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040110, NM_001293163, NM_001293164, NM_005011
• Synonyms: ALPHA-PAL
• Summary: 'This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]'